Regulations last checked for updates: Nov 25, 2024

Title 21 - Food and Drugs last revised: Nov 21, 2024
§ 556.113 - Ceftiofur.

(a) Acceptable daily intake and acute reference dose—(1) Acceptable daily intake (ADI). The ADI for total residue of ceftiofur is 30 µg/kg of body weight per day.

(2) Acute reference dose (ARfD). The ARfD for total residue of ceftiofur is 0.830 mg/kg of body weight.

(b) Tolerances. The tolerances for desfuroylceftiofur (marker residue) are:

(1) Cattle. (i) Kidney (target tissue): 0.4 ppm.

(ii) Liver: 2 ppm.

(iii) Muscle: 1 ppm.

(iv) Milk: 0.1 ppm.

(2) Chickens and turkeys. Edible tissues (excluding eggs): Not required.

(3) Goats. (i) Kidney (target tissue): 8 ppm.

(ii) Liver: 2 ppm.

(iii) Muscle: 1 ppm.

(iv) Milk: 0.1 ppm.

(4) Sheep. Edible tissues (excluding milk): Not required.

(5) Swine. (i) Kidney (target tissue): 0.25 ppm.

(ii) Liver: 3 ppm.

(iii) Muscle: 2 ppm.

(c) Related conditions of use. See §§ 522.313a, 522.313b, 522.313c, and 526.313 of this chapter.

authority: 21 U.S.C. 342,360b,371
source: 84 FR 32993, July 11, 2019, unless otherwise noted.
cite as: 21 CFR 556.113