§ 283a–3.
(c)
Longitudinal studies
After consultation with the Office of Research on Women’s Health, the Director of NIH, acting through the appropriate national research institutes, shall in carrying out subsection (a) conduct or support one or more longitudinal studies to determine the incidence of the following diseases or disorders in the indicated populations and the relationship of DES to the diseases or disorders:
(1)
In the case of women to whom (on or after January 1, 1938) DES was administered while the women were pregnant, the incidence of all diseases and disorders (including breast cancer, gynecological cancers, and impairments of the immune system, including autoimmune disease).
(2)
In the case of women exposed to DES in utero, the incidence of clear cell cancer (including recurrences), the long-term health effects of such cancer, and the effects of treatments for such cancer.
(3)
In the case of men and women exposed to DES in utero, the incidence of all diseases and disorders (including impairments of the reproductive and autoimmune systems).
(4)
In the case of children of men or women exposed to DES in utero, the incidence of all diseases and disorders.
([July 1, 1944, ch. 373], title IV, § 403D, formerly § 403A, as added [Pub. L. 102–409, § 2], Oct. 13, 1992, [106 Stat. 2092]; amended [Pub. L. 105–340, title I, § 101(a)], Oct. 31, 1998, [112 Stat. 3191]; renumbered § 403C and amended [Pub. L. 109–482, title I], §§ 103(b)(2), 104(a)(1), Jan. 15, 2007, [120 Stat. 3687], 3689; renumbered § 403D, [Pub. L. 110–85, title XI, § 1104(4)], Sept. 27, 2007, [121 Stat. 975].)