Regulations last checked for updates: Nov 23, 2024

Title 15 - Commerce and Foreign Trade last revised: Oct 25, 2024
Appendix - Supplement No. 1 to Part 712—Schedule 1 Chemicals
CAS
registry No.
A. Toxic Chemicals:
1. Family: O-Alkyl(≤C10, incl. cycloalkyl) alkyl (Me, Et, n-Pr or i-Pr)- phosphonofluoridates
Not limited to the following examples:
Sarin: O-Isopropyl methylphosphonofluoridate107-44-8
Soman: O-Pinacolyl methylphosphonofluoridate96-64-0
2. Family: O-Alkyl (≤C10, incl. cycloalkyl) N,N-dialkyl (Me, Et, n-Pr or i-Pr) phosphoramidocyanidates
Not limited to the following example:
Tabun: O-Ethyl N,N-dimethyl phosphoramidocyanidate77-81-6
3. Family: O-Alkyl (H or ≤C10, incl. cycloalkyl) S-2-dialkyl (Me, Et, n-Pr or i-Pr)-aminoethyl alkyl (Me, Et, n-Pr or i-Pr) phosphonothiolates and corresponding alkylated or protonated salts
Not limited to the following example:
VX: O-Ethyl S-2-diisopropylaminoethyl methyl phosphonothiolate50782-69-9
4. Sulfur mustards:
2-Chloroethylchloromethylsulfide2625-76-5
Mustard gas: Bis(2-chloroethyl)sulfide505-60-2
Bis(2-chloroethylthio)methane63869-13-6
Sesquimustard: 1,2-Bis(2-chloroethylthio)ethane3563-36-8
1,3-Bis(2-chloroethylthio)-n-propane63905-10-2
1,4-Bis(2-chloroethylthio)-n-butane142868-93-7
1,5-Bis(2-chloroethylthio)-n-pentane142868-94-8
Bis(2-chloroethylthiomethyl)ether63918-90-1
O-Mustard: Bis(2-chloroethylthioethyl)ether63918-89-8
5. Lewisites:
Lewisite 1: 2-Chlorovinyldichloroarsine541-25-3
Lewisite 2: Bis(2-chlorovinyl)chloroarsine40334-69-8
Lewisite 3: Tris(2-chlorovinyl)arsine40334-70-1
6. Nitrogen mustards:
HN1: Bis(2-chloroethyl)ethylamine538-07-8
HN2: Bis(2-chloroethyl)methylamine51-75-2
HN3: Tris(2-chloroethyl)amine555-77-1
7. Saxitoxin35523-89-8
8. Ricin9009-86-3
13. Family: Р-alkyl (H or ≤C10, incl. cycloalkyl) N-(1-(dialkyl(≤C10, incl. cycloalkyl)amino))alkylidene(H or ≤C10, incl. cycloalkyl) phosphonamidic fluorides and corresponding alkylated or protonated salts
Not limited to the following examples:
N-(1-(di-n-decylamino)-n-decylidene)-P-decylphosphonamidic fluoride2387495-99-8
Methyl-(1-(diethylamino)ethylidene)phosphonamidofluoridate2387496-12-8
14. Family: O-alkyl (H or ≤C10, incl. cycloalkyl) N-(1-(dialkyl(≤C10, incl. cycloalkyl)amino))alkylidene(H or ≤C10, incl. cycloalkyl) phosphoramidofluoridates and corresponding alkylated or protonated salts
Not limited to the following examples:
O-n-Decyl N-(1-(di-n-decylamino)-n decylidene)phosphoramidofluoridate2387496-00-4
Methyl (1-(diethylamino)ethylidene)phosphoramidofluoridate2387496-04-8
Ethyl (1-(diethylamino)ethylidene)phosphoramidofluoridate2387496-06-0
15. Methyl-(bis(diethylamino)methylene)phosphonamidofluoridate2387496-14-0
16. Carbamates (quaternaries and bisquaternaries of dimethylcarbamoyloxypyridines)
16.1. Family: Quaternaries of dimethylcarbamoyloxypyridines: 1-[N,N-dialkyl(≤C10)-N-(n-(hydroxyl, cyano, acetoxy)alkyl(≤C10)) ammonio]-n-[N-(3-dimethylcarbamoxy-α-picolinyl)-N,N-dialkyl(≤C10) ammonio]decane dibromide (n=1-8)
Not limited to the following example:
1-[N,N-dimethyl-N-(2-hydroxy)ethylammonio]-10-[N-(3-dimethylcarbamoxy-α-picolinyl)-N,N-dimethylammonio]decane dibromide77104-62-2
16.2. Family: Bisquaternaries of dimethylcarbamoyloxypyridines:1,n-Bis[N-(3-dimethylcarbamoxy-α-picolyl)-N,N-dialkyl(≤C10) ammonio]-alkane-(2,(n-1)-dione) dibromide (n=2-12)
Not limited to the following example:
1,10-Bis[N-(3-dimethylcarbamoxy-α-picolyl)-N-ethyl-N- methylammonio]decane-2,9-dione dibromide77104-00-8
B. Precursors:
9. Family: Alkyl (Me, Et, n-Pr or i-Pr) phosphonyldifluorides
Not limited to the following example:
DF: Methylphosphonyldifluoride676-99-3
10. Family: O-Alkyl (H or ≤C10, incl. cycloalkyl) O-2-dialkyl (Me, Et, n-Pr or i-Pr)-aminoethyl alkyl (Me, Et, n-Pr or i-Pr) phosphonites and corresponding alkylated or protonated salts
Not limited to the following example:
QL: O-Ethyl O-2-diisopropylaminoethyl methylphosphonite57856-11-8
11. Chlorosarin: O-Isopropyl methylphosphonochloridate1445-76-7
12. Chlorosoman: O-Pinacolyl methylphosphonochloridate7040-57-5

Notes to Supplement No. 1

Note 1: Note that the following Schedule 1 chemicals are controlled for export purposes under the Export Administration Regulations (see part 774 of the EAR, the Commerce Control List): Saxitoxin (35523-89-8) and Ricin (9009-86-3).

Note 2: All Schedule 1 chemicals not listed in Note 1 to this Supplement are controlled for export purposes by the Directorate of Defense Trade Controls of the Department of State under the International Traffic in Arms Regulations (22 CFR parts 120 through 130).

Note 3: The numerical sequence of the “Schedule 1” Toxic Chemicals and Precursors is not consecutive so as to align with the December 23, 2019, consolidated textual changes to “Schedule 1” of the Annex on Chemicals to the Chemical Weapons Convention (CWC), which reflect the decisions adopted by the CWC Conference of the States Parties in November 2019.

[71 FR 24929, Apr. 27, 2006, as amended at 86 FR 941, Jan. 7, 2021]
authority: 22 U.S.C. 6701
source: 71 FR 24929, Apr. 27, 2006, unless otherwise noted.